Structure of PDB 4wu5 Chain A Binding Site BS01

Receptor Information
>4wu5 Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFG
CDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAA
HVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>4wu5 Chain C (length=8) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RYPLTFGW
Receptor-Ligand Complex Structure
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PDB4wu5 Crystal structure of Nef134-8(wt) epitope presented by HLA-A24
Resolution2.4 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 T73 N77 Y84 L95 F99 Y123 T143 K146 W147 V152 Q155 Q156 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 T73 N77 Y84 L95 F99 Y123 T143 K146 W147 V152 Q155 Q156 Y159 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4wu5, PDBe:4wu5, PDBj:4wu5
PDBsum4wu5
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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