Structure of PDB 4wsi Chain A Binding Site BS01

Receptor Information
>4wsi Chain A (length=372) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSG
LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPA
KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY
REGDEDNQPLAGLVPGKEEILTYEEMSLYHQPANRKRPIILIGPQNCGQN
ELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAG
KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY
IIFIAPPSQERLRALLELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ
ELLRLINKLDTEPQWVPSTWLR
Ligand information
>4wsi Chain X (length=18) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PRLEMDNVLKPPPEERLI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4wsi Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		P266 L267 A269 T270 V271 N273 S281 R282 N315 F318 L321 P365 E368 L369 P512 R516 D527 Y528 F551 Y556 S576 R578
Binding residue
(residue number reindexed from 1)		P23 L24 A26 T27 V28 N30 S38 R39 N72 F75 L78 P122 E125 L126 P219 R223 D234 Y235 F258 Y263 S283 R285
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4wsi, PDBe:4wsi, PDBj:4wsi
PDBsum4wsi
PubMed25385611
UniProtQ8N3R9|PALS1_HUMAN Protein PALS1 (Gene Name=PALS1)

[Back to BioLiP]