Structure of PDB 4wng Chain A Binding Site BS01
Receptor Information
>4wng Chain A (length=330) Species:
9606
(Homo sapiens) [
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GSMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQ
LGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGN
FDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGGEFPEEV
RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA
HEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ
LKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRA
CWSLGNAYTALGNHDQAMHFAEKHLEISRE
Ligand information
>4wng Chain B (length=18) Species:
9606
(Homo sapiens) [
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HMEMEPETMETKSVTDYF
Receptor-Ligand Complex Structure
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PDB
4wng
Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN
Resolution
2.11 Å
Binding residue
(original residue number in PDB)
E25 A56 Q60 N63 F66 Y67 D81 G93 K96 N100 N103 K106 R136 Y139 H146 R196 N200 N203 L207 R221 R235 R236 N240
Binding residue
(residue number reindexed from 1)
E15 A46 Q50 N53 F56 Y57 D71 G83 K86 N90 N93 K96 R126 Y129 H136 R179 N183 N186 L190 R204 R218 R219 N223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4wng
,
PDBe:4wng
,
PDBj:4wng
PDBsum
4wng
PubMed
25664792
UniProt
P81274
|GPSM2_HUMAN G-protein-signaling modulator 2 (Gene Name=GPSM2)
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