Structure of PDB 4wnf Chain A Binding Site BS01
Receptor Information
>4wnf Chain A (length=255) Species:
9606
(Homo sapiens) [
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SMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQL
GNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNF
DEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPPQDVGE
FPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFR
DAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL
LLARQ
Ligand information
>4wnf Chain B (length=18) Species:
9606
(Homo sapiens) [
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HMEMEPETMETKSVTDYF
Receptor-Ligand Complex Structure
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PDB
4wnf
Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
E25 Q60 N63 F66 D81 G93 K96 N100 N103 K106 H121 R136 Y139 H146 R196 N200 N203 Y206 R221 R235 R236 N240
Binding residue
(residue number reindexed from 1)
E14 Q49 N52 F55 D70 G82 K85 N89 N92 K95 H110 R125 Y128 H135 R184 N188 N191 Y194 R209 R223 R224 N228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4wnf
,
PDBe:4wnf
,
PDBj:4wnf
PDBsum
4wnf
PubMed
25664792
UniProt
P81274
|GPSM2_HUMAN G-protein-signaling modulator 2 (Gene Name=GPSM2)
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