Structure of PDB 4wne Chain A Binding Site BS01
Receptor Information
>4wne Chain A (length=326) Species:
9606
(Homo sapiens) [
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SMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQL
GNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNF
DEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFFPEEVRDAL
QAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQR
LLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDR
AVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSL
GNAYTALGNHDQAMHFAEKHLEISRE
Ligand information
>4wne Chain B (length=19) Species:
9606
(Homo sapiens) [
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DHMEMEPETMETKSVTDYF
Receptor-Ligand Complex Structure
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PDB
4wne
Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
E25 K52 A56 Q60 N63 D81 G93 K96 N100 N103 K106 H121 R136 Y139 H146 R196 N200 N203 Y206 L207 R221 R235 R236 N240
Binding residue
(residue number reindexed from 1)
E14 K41 A45 Q49 N52 D70 G82 K85 N89 N92 K95 H110 R125 Y128 H135 R175 N179 N182 Y185 L186 R200 R214 R215 N219
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4wne
,
PDBe:4wne
,
PDBj:4wne
PDBsum
4wne
PubMed
25664792
UniProt
P81274
|GPSM2_HUMAN G-protein-signaling modulator 2 (Gene Name=GPSM2)
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