Structure of PDB 4wc3 Chain A Binding Site BS01

Receptor Information

>4wc3 Chain A (length=367) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MVGQIAKEMGLRAYIVGGVVRDILLGKEVWDVDFVVEGNAIELAKELARR
HGVNVHPFPEFGTAHLKIGKLKLEFATARRETEPASLKEDLIRRDFTINA
MAISVNLEDYGTLIDYFGGLRDLKDKVIRVLHPVSFIEDPVRILRALRFA
GRLNFKLSRSTEKLLKQAVNLGLLKEAPRGRLINEIKLALREDRFLEILE
LYRKYRVLEEIIEGFQWNEKVLQKLYALRKVVDWHALEFSEERIDYGWLY
LLILISNLDYERGKHFLEEMSAPSWVRETYKFMKFKLGSLKEELKKAKEN
YEVYRLLKPLHTSVLLLLMLEEELKEKIKLYLEKLRKVKLPKEKIEELKK
GKELGERIEELKREIMN

Ligand information

>4wc3 Chain B (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggccagguagcucaguugguagagcacuggacugaaaauccaggugucgg
cgguucgauuccgccccuggccacca

<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wc3 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	D33 F61 R103 R104 D105 N109 D149 R152 G190 R191 N194 K197 S281 S284 G365 K366 G369
Binding residue (residue number reindexed from 1)	D33 F61 R93 R94 D95 N99 D139 R142 G180 R181 N184 K187 S271 S274 G351 K352 G355

Enzymatic activity

Enzyme Commision number

2.7.7.-

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0016779	nucleotidyltransferase activity

	Biological Process
GO:0006396	RNA processing

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Molecular Function

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Biological Process

External links

PDB	RCSB:4wc3, PDBe:4wc3, PDBj:4wc3
PDBsum	4wc3
PubMed	25914059
UniProt	O66728\|AATNT_AQUAE A-adding tRNA nucleotidyltransferase (Gene Name=aq_411)

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