Structure of PDB 4w8p Chain A Binding Site BS01

Receptor Information
>4w8p Chain A (length=301) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEA
MTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQA
GQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALC
NSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRA
QCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTM
LESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAP
G
Ligand information
>4w8p Chain B (length=21) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NEDIDQMFSTLLGEMDLLTQS
Receptor-Ligand Complex Structure
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PDB4w8p Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		A1495 T1496 A1499 S1503 C1506 N1507 R1510 A1529 T1536 V1540 K1544
Binding residue
(residue number reindexed from 1)		A139 T140 A143 S147 C150 N151 R154 A173 T180 V184 K188
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4w8p, PDBe:4w8p, PDBj:4w8p
PDBsum4w8p
PubMed25465129
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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