Structure of PDB 4w5a Chain A Binding Site BS01
Receptor Information
>4w5a Chain A (length=128) Species:
9606
(Homo sapiens) [
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GPLGSMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDIS
RDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDEN
NQWYCYICHPEPLLDLVTACNSVYENLE
Ligand information
>4w5a Chain C (length=11) Species:
9606
(Homo sapiens) [
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ARTKQTARKST
Receptor-Ligand Complex Structure
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PDB
4w5a
ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
Y43 D48 M56 E58 A64 E65 G66 G67 N68 L69 C71 D73
Binding residue
(residue number reindexed from 1)
Y43 D48 M56 E58 A64 E65 G66 G67 N68 L69 C71 D73
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
External links
PDB
RCSB:4w5a
,
PDBe:4w5a
,
PDBj:4w5a
PDBsum
4w5a
PubMed
25538301
UniProt
P46100
|ATRX_HUMAN Transcriptional regulator ATRX (Gene Name=ATRX)
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