Structure of PDB 4v29 Chain A Binding Site BS01

Receptor Information
>4v29 Chain A (length=165) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDDLLGLLRIRIKRGVNLAVRDISSSDPYVVVKMGKQKLKTRVINKDVNP
EWNEDLTLSVTDSNLTVLLTVYDHDMFSKDDKMGDAEFEIKPYIEALRMQ
LDGLPSGTIVTTVKPSRRNCLAEESRVTWVDGKLVQDLVLRLRHVECGEV
EAQLQWIDLPGSKGL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4v29 Chain A Residue 1178 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4v29 C2-Domain Abscisic Acid-Related Proteins Mediate the Interaction of Pyr/Pyl/Rcar Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic Acid Sensitivity in Arabidopsis.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		R33 D34 D85 D87
Binding residue
(residue number reindexed from 1)		R21 D22 D73 D75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008289 lipid binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006952 defense response
GO:0009651 response to salt stress
GO:0009738 abscisic acid-activated signaling pathway
GO:0009789 positive regulation of abscisic acid-activated signaling pathway
GO:1900426 positive regulation of defense response to bacterium
GO:1901002 positive regulation of response to salt stress
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v29, PDBe:4v29, PDBj:4v29
PDBsum4v29
PubMed25465408
UniProtQ9LVH4|CAR4_ARATH Protein C2-DOMAIN ABA-RELATED 4 (Gene Name=CAR4)

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