Structure of PDB 4un8 Chain A Binding Site BS01

Receptor Information
>4un8 Chain A (length=184) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIA
PLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNM
REQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHL
DDHRHGVYVLNISLRDRIKFVHTILSSHLNPLPP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4un8 Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		G20 D21 G22 Y25 Y29 R33 R37 T41 K43 T76 R77 E117 R124 T150 H152 D154 R157 S166 L167
Binding residue
(residue number reindexed from 1)		G17 D18 G19 Y22 Y26 R30 R34 T38 K40 T73 R74 E114 R121 T147 H149 D151 R154 S163 L164
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function
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Biological Process
External links
PDB RCSB:4un8, PDBe:4un8, PDBj:4un8
PDBsum4un8
PubMed25486305
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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