Structure of PDB 4udc Chain A Binding Site BS01
Receptor Information
>4udc Chain A (length=248) Species:
9606
(Homo sapiens) [
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TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWA
KAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLI
INEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKD
GLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV
VENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>4udc Chain B (length=13) Species:
9606
(Homo sapiens) [
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ENALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
4udc
Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
V575 K576 K579 R585 L589 M593 Q597 E751 M752 E755 N759
Binding residue
(residue number reindexed from 1)
V47 K48 K51 R57 L61 M65 Q69 E223 M224 E227 N231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4udc
,
PDBe:4udc
,
PDBj:4udc
PDBsum
4udc
PubMed
26602186
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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