Structure of PDB 4uci Chain A Binding Site BS01

Receptor Information
>4uci Chain A (length=361) Species: 162145 (human metapneumovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPTEQLAYFPKITFERLKNGKLTRNYMILLPWQHVNRYNFVFSSTGCKVS
LKTCIGKLMKDLNPKVLYFIGEGAGNWMARTACEYPDIKFVYRSLKDDLD
HHYPLEYQRVIGELSRIIDSGEGLSMETTDATQKTHWDLIHRVSKDALLI
TLCDAEFKDRDDFFKMVILWRKHVLSCRICTTYGTDLYLFAKYHAKDCNV
KLPFFVRSVATFIMQGSKLSGSECYILLTLGHHNNLPCHGEIQNSKMKIA
VCNDFYAAKKLDNKSIEANCKSLLSGLRIPINKKELNRQRRLLTKWLTNK
ANTIIDWLEHILNSPKGELNYDFFEALENTYPNMIKLIDNLGNAEIKKLI
KVTGYMLVSKK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4uci Chain A Residue 2408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4uci X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Resolution2.21 Å
Binding residue
(original residue number in PDB)		H1766 H1798 C1802 C1805
Binding residue
(residue number reindexed from 1)		H141 H173 C177 C180
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.375: NNS virus cap methyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.88: GDP polyribonucleotidyltransferase.
External links