Structure of PDB 4u87 Chain A Binding Site BS01

Receptor Information
>4u87 Chain A (length=191) Species: 1311 (Streptococcus agalactiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEKARYFTFLLYPESIPSDWELKLETLGVPMAISPLHDKDKAHYHVLYIA
KNPVTADSVRKKIKLLLGEKSLAMVQVVLNVENMYLYLTHESKDAIAKKK
HVYDKADIKLINNFDIDRYVTLDVEEKTELFNVVVSLIRAYTLQNIFDLY
DFIDENGETYGLTINLVNEVIAGKTGFMKLLFDGAYQRSKR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4u87 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4u87 Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		H39 D42 H55 H57 H102
Binding residue
(residue number reindexed from 1)		H37 D40 H43 H45 H90
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
GO:0042802 identical protein binding
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005727 extrachromosomal circular DNA

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u87, PDBe:4u87, PDBj:4u87
PDBsum4u87
PubMed26875695
UniProtP13921|REPB_STRAG Replication protein RepB (Gene Name=repB)

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