Structure of PDB 4u1s Chain A Binding Site BS01

Receptor Information
>4u1s Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEA
ARVAEQLRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
Ligand information
>4u1s Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FPRPWLHGL
Receptor-Ligand Complex Structure
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PDB4u1s A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Resolution1.76 Å
Binding residue
(original residue number in PDB)		Y7 R62 N63 Q70 T73 S77 Y84 Y99 N114 Y116 S143 V152 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y8 R63 N64 Q71 T74 S78 Y85 Y100 N115 Y117 S144 V153 L157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4u1s, PDBe:4u1s, PDBj:4u1s
PDBsum4u1s
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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