Structure of PDB 4u1n Chain A Binding Site BS01

Receptor Information
>4u1n Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSHSMRYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEA
ARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
Ligand information
>4u1n Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RPQVPLRPM
Receptor-Ligand Complex Structure
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PDB4u1n A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Resolution1.77 Å
Binding residue
(original residue number in PDB)		Y7 R62 N63 A69 Q70 T73 E76 S77 Y84 Y99 Y116 T143 W147 A150 D156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y8 R63 N64 A70 Q71 T74 E77 S78 Y85 Y100 Y117 T144 W148 A151 D157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4u1n, PDBe:4u1n, PDBj:4u1n
PDBsum4u1n
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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