Structure of PDB 4u1j Chain A Binding Site BS01

Receptor Information
>4u1j Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEA
ARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
Ligand information
>4u1j Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TPQDLNTML
Receptor-Ligand Complex Structure
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PDB4u1j A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Resolution1.38 Å
Binding residue
(original residue number in PDB)
Y7 R62 N63 I66 Y67 Q70 T73 S77 N80 Y84 Y99 Y123 T143 W147 D156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 R63 N64 I67 Y68 Q71 T74 S78 N81 Y85 Y100 Y124 T144 W148 D157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4u1j, PDBe:4u1j, PDBj:4u1j
PDBsum4u1j
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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