Structure of PDB 4u1i Chain A Binding Site BS01
Receptor Information
>4u1i Chain A (length=278) Species:
9606
(Homo sapiens) [
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MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEA
ARVAEQDRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
Ligand information
>4u1i Chain C (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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TPQDLNTML
Receptor-Ligand Complex Structure
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PDB
4u1i
A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
Y7 R62 N63 I66 Y67 Q70 T73 S77 N80 Y84 Y99 S143 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 R63 N64 I67 Y68 Q71 T74 S78 N81 Y85 Y100 S144 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4u1i
,
PDBe:4u1i
,
PDBj:4u1i
PDBsum
4u1i
PubMed
25808313
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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