Structure of PDB 4u0c Chain A Binding Site BS01

Receptor Information

>4u0c Chain A (length=210) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PIVQNQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQDLN
TMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHIAPGQMREPRGSDIAG
TTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQG
PKEPFRDYVDRFYKTLRAEQASQEVKTETLLVQNANPDCKTILKALGPGA
TLEEMMTACQ

Ligand information

>4u0c Chain B (length=9) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

SPSGVFTFG

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4u0c Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Resolution	1.77 Å
Binding residue (original residue number in PDB)	N53 L56 N57 M66 G106
Binding residue (residue number reindexed from 1)	N50 L53 N54 M63 G100

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0016032	viral process

View graph for
Biological Process

External links

PDB	RCSB:4u0c, PDBe:4u0c, PDBj:4u0c
PDBsum	4u0c
PubMed	25356722
UniProt	P12493\|GAG_HV1N5 Gag polyprotein (Gene Name=gag)

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