Structure of PDB 4tyy Chain A Binding Site BS01

Receptor Information
>4tyy Chain A (length=505) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKLIHVPKSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPI
LSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTR
DLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVI
ATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNE
KNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHE
RIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLC
SILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGM
DFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRE
LEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSC
IKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKA
MFEIR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tyy Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		P188 R190 G220 F224 T242 G244 R245 D248 R271 T382 V383 K384 H407 G408 R415 T433 V435 S535
Binding residue
(residue number reindexed from 1)		P98 R100 G130 F134 T152 G154 R155 D158 R181 T292 V293 K294 H317 G318 R325 T343 V345 S445
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:4tyy, PDBe:4tyy, PDBj:4tyy
PDBsum4tyy
PubMed25497230
UniProtP15424|MS116_YEAST ATP-dependent RNA helicase MSS116, mitochondrial (Gene Name=MSS116)

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