Structure of PDB 4tx8 Chain A Binding Site BS01

Receptor Information

>4tx8 Chain A (length=374) Species: 243365 (Chromobacterium violaceum ATCC 12472)

ACPGWAEGTAYKVGDVVSYNNANYTALVAHTAYVGANWNPAASPTLWTPG
GSCGNTVPFAKHALVGYWHNFANPSGSAFPLSQVSADWDVIVVAFADDAG
NGNVSFTLDPAAGSAAQFIQDIRAQQAKGKKVVLSLGGQNGSVTLNNATQ
VQNFVNSLYGILTQYGFDGIDLDLESGSGIVVGAPVVSNLVSAVKQLKAK
IGPNFYLSMAPEHPYVQGGFVAYGGNWGAYLPIIDGLRDDLSVIHVQYYN
NGGLYTPYSTGVLAEGSADMLVGGSKMLIEGFPIANGASGSFKGLRPDQV
AFGVPSGRSSANSGFVTADTVAKALTCLTTLQGCGSVKPAQAYPAFRGVM
TWSINWDRRDGYTFSRPVAASLRQ

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 4tx8 Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4tx8 Crystal Structure of a Family GH18 Chitinase from Chromobacterium violaceum
• Resolution: 2.17 Å
• Binding residue (original residue number in PDB): R330 A333
• Binding residue (residue number reindexed from 1): R308 A311
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.2.1.14: chitinase.

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0008061 chitin binding
• GO:0030246 carbohydrate binding

Biological Process

• GO:0005975 carbohydrate metabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:4tx8, PDBe:4tx8, PDBj:4tx8
• PDBsum: 4tx8
• UniProt: Q7NTW8