Structure of PDB 4tvc Chain A Binding Site BS01

Receptor Information
>4tvc Chain A (length=1036) Species: 1245 (Leuconostoc mesenteroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVT
EGHYGTITAWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDD
KLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNG
ALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDMSTNAFST
KNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLI
TVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIE
RRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGG
YLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYL
MNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAK
ANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNM
LQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGA
DWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRM
YYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKS
VRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHK
NQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIR
GVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNL
IYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDH
TFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMAD
VVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKY
AGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPAD
VAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKL
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain4tvc Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tvc Structural Insights into the Carbohydrate Binding Ability of an alpha-(12) Branching Sucrase from Glycoside Hydrolase Family 70.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		K1881 K1898
Binding residue
(residue number reindexed from 1)		K92 K109
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4tvc, PDBe:4tvc, PDBj:4tvc
PDBsum4tvc
PubMed26865636
UniProtQ8G9Q2

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