Structure of PDB 4tv1 Chain A Binding Site BS01

Receptor Information
>4tv1 Chain A (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tv1 A structural perspective on nuclear receptors as targets of environmental compounds.
Resolution1.85 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 D226 E230
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4tv1, PDBe:4tv1, PDBj:4tv1
PDBsum4tv1
PubMed25500867
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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