Structure of PDB 4tuz Chain A Binding Site BS01

Receptor Information
>4tuz Chain A (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tuz A structural perspective on nuclear receptors as targets of environmental compounds.
Resolution1.9 Å
Binding residue
(original residue number in PDB)
I358 L372 D538 E542
Binding residue
(residue number reindexed from 1)
I54 L68 D226 E230
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4tuz, PDBe:4tuz, PDBj:4tuz
PDBsum4tuz
PubMed25500867
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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