Structure of PDB 4tu0 Chain A Binding Site BS01

Receptor Information
>4tu0 Chain A (length=162) Species: 37124 (Chikungunya virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHAPSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNS
ATPVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTR
LGVNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEW
EKKISEAIQMRT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tu0 CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
Resolution2.3 Å
Binding residue
(original residue number in PDB)
D12 I13 G34 V35 T113 G114 V115 R146 D147 W150
Binding residue
(residue number reindexed from 1)
D12 I13 G34 V35 T113 G114 V115 R146 D147 W150
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
External links
PDB RCSB:4tu0, PDBe:4tu0, PDBj:4tu0
PDBsum4tu0
PubMed
UniProtQ8JUX6|POLN_CHIKS Polyprotein P1234

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