Structure of PDB 4tqr Chain A Binding Site BS01
Receptor Information
>4tqr Chain A (length=342) Species:
273057
(Saccharolobus solfataricus P2) [
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MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEA
RKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIE
IASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVF
AKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGIN
KLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRIVT
MKRNSRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGR
TFPHGISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFIE
Ligand information
>4tqr Chain P (length=12) [
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gggggaaggatt
Receptor-Ligand Complex Structure
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PDB
4tqr
Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Resolution
1.58 Å
Binding residue
(original residue number in PDB)
G185 G187 I189 T190 D294 I295 V296 S297 R298
Binding residue
(residue number reindexed from 1)
G185 G187 I189 T190 D294 I295 V296 S297 R298
Enzymatic activity
Enzyme Commision number
2.7.7.7
: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0003677
DNA binding
GO:0003684
damaged DNA binding
GO:0003887
DNA-directed DNA polymerase activity
GO:0046872
metal ion binding
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0006281
DNA repair
GO:0006974
DNA damage response
GO:0042276
error-prone translesion synthesis
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4tqr
,
PDBe:4tqr
,
PDBj:4tqr
PDBsum
4tqr
PubMed
25569151
UniProt
Q97W02
|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)
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