Structure of PDB 4tpg Chain A Binding Site BS01

Receptor Information
>4tpg Chain A (length=459) Species: 211586 (Shewanella oneidensis MR-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSAC
AALIYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMF
SALGVIVVGNGLFKPNAGNLVRKIYESKIDSAFTIYYMAVNVGSTFSMLL
TPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMHKSLANYGSEP
DTRPVNKKSLAIVLALAALSVVASAIILEYEDVARVFVYAAGVAVLGIFF
HLIRPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVF
GTHLWTWSPAQFQALNPIWIMVLSPVLAWIAAKFALGFAVVAIGFFIYGF
AGQFAVNGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYFMMGAYFVAS
GISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGVAAVVCTIIALA
VLPLMRRLT
Ligand information
Receptor-Ligand Complex Structure
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PDB4tpg Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
Resolution3.91 Å
Binding residue
(original residue number in PDB)		R25 Y28 Y29 K121 Y147 N151
Binding residue
(residue number reindexed from 1)		R18 Y21 Y22 K114 Y137 N141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015333 peptide:proton symporter activity
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042937 tripeptide transmembrane transporter activity
GO:0071916 dipeptide transmembrane transporter activity
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015833 peptide transport
GO:0035442 dipeptide transmembrane transport
GO:0042939 tripeptide transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tpg, PDBe:4tpg, PDBj:4tpg
PDBsum4tpg
PubMed25064511
UniProtQ8EHE6

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