Structure of PDB 4tme Chain A Binding Site BS01

Receptor Information
>4tme Chain A (length=217) Species: 451755 (Clostridium perfringens E str. JGS1987) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKNDLIRPNVLSVKIISNVSPEMAKKLELEPHHKSLGLITADCDDVTYTA
LDEATKAAEVDVVYARSMYAGAGNASTKLAGEVIGILAGPSPAEVRSGLN
ATLDFIDSGVGFVSANEDDSICYYAQCVSRTGSYLSKTAGIREGEALAYL
VAPPLEAMYALDAALKAADVEMCEFFAPPTETNFAGALLTGSQSACKAAC
DAFAEAVQSVASNPLGF
Ligand information
Ligand IDETA
InChIInChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
InChIKeyHZAXFHJVJLSVMW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370NCCO
ACDLabs 12.01OCCN
OpenEye OEToolkits 1.7.0C(CO)N
FormulaC2 H7 N O
NameETHANOLAMINE
ChEMBLCHEMBL104943
DrugBankDB03994
ZINCZINC000008214617
PDB chain4tme Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4tme An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D45 F176 T180
Binding residue
(residue number reindexed from 1)		D45 F176 T180
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
GO:0031419 cobalamin binding
GO:0046872 metal ion binding
Cellular Component
GO:0031469 bacterial microcompartment

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4tme, PDBe:4tme, PDBj:4tme
PDBsum4tme
PubMed25752492
UniProtQ8XLZ0|EUTL_CLOPE Bacterial microcompartment shell protein EutL (Gene Name=eutL)

[Back to BioLiP]