Structure of PDB 4tk4 Chain A Binding Site BS01

Receptor Information
>4tk4 Chain A (length=413) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFP
ASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPC
GADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGEC
VLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLP
GKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVII
TSGGVKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFA
LPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY
HRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELH
KGEVVDVMVIGRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tk4 Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Resolution3.601 Å
Binding residue
(original residue number in PDB)		D327 F330 R653 Y673 P713 D729
Binding residue
(residue number reindexed from 1)		D8 F11 R330 Y350 P390 D406
Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:4tk4, PDBe:4tk4, PDBj:4tk4
PDBsum4tk4
PubMed25531214
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

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