Structure of PDB 4rtw Chain A Binding Site BS01
Receptor Information
>4rtw Chain A (length=57) Species:
9031
(Gallus gallus) [
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TFVALYDYVSRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGRTGYIPS
NYVAPSD
Ligand information
>4rtw Chain B (length=7) Species:
32630
(synthetic construct) [
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APPLPPR
Receptor-Ligand Complex Structure
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PDB
4rtw
Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
Resolution
1.24 Å
Binding residue
(original residue number in PDB)
Y90 Y92 R95 T96 D99 E115 W118 P133 N135 Y136
Binding residue
(residue number reindexed from 1)
Y6 Y8 R11 T12 D15 E31 W34 P49 N51 Y52
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:4rtw
,
PDBe:4rtw
,
PDBj:4rtw
PDBsum
4rtw
PubMed
UniProt
P00523
|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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