Structure of PDB 4rqz Chain A Binding Site BS01

Receptor Information
>4rqz Chain A (length=272) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYI
ITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTI
PINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQ
TDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLA
TKIMDKLIRDGRVIRGYIVVNDGPAANAGDLIISVDNKPASALETMDQVA
EIRPGSVIPVVVTLQVTIQEYP
Ligand information
Receptor-Ligand Complex Structure
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PDB4rqz A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y258 M319 V322
Binding residue
(residue number reindexed from 1)		Y217 M246 V249
Enzymatic activity
Enzyme Commision number 3.4.21.107: peptidase Do.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4rqz, PDBe:4rqz, PDBj:4rqz
PDBsum4rqz
PubMed25703375
UniProtP0AEE3|DEGS_ECOLI Serine endoprotease DegS (Gene Name=degS)

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