Structure of PDB 4rqi Chain A Binding Site BS01

Receptor Information
>4rqi Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLG
KEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTE
FTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLR
NDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKK
ALK
Ligand information
Receptor-Ligand Complex Structure
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PDB4rqi A higher-order entity formed by the flexible assembly of RAP1 with TRF2.
Resolution2.4405 Å
Binding residue
(original residue number in PDB)		R80 Q84 S98 L101 R102 Q105 R109 C118 S119 F120 D121 M122 S131
Binding residue
(residue number reindexed from 1)		R38 Q42 S56 L59 R60 Q63 R67 C76 S77 F78 D79 M80 S89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042162 telomeric DNA binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0000723 telomere maintenance
GO:0031848 protection from non-homologous end joining at telomere
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rqi, PDBe:4rqi, PDBj:4rqi
PDBsum4rqi
PubMed26748096
UniProtQ15554|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)

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