Structure of PDB 4roj Chain A Binding Site BS01
Receptor Information
>4roj Chain A (length=103) Species:
9606
(Homo sapiens) [
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DYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDE
VKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP
YKS
Ligand information
>4roj Chain D (length=8) Species:
9606
(Homo sapiens) [
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PPCYMDVI
Receptor-Ligand Complex Structure
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PDB
4roj
Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
R680 R698 R700 K718 H719 K721 F756
Binding residue
(residue number reindexed from 1)
R14 R32 R34 K52 H53 K55 F90
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4roj
,
PDBe:4roj
,
PDBj:4roj
PDBsum
4roj
PubMed
UniProt
P52735
|VAV2_HUMAN Guanine nucleotide exchange factor VAV2 (Gene Name=VAV2)
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