Structure of PDB 4rfn Chain A Binding Site BS01

Receptor Information
>4rfn Chain A (length=337) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWKDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIHLENVTENF
NMWKNNMVEQMQEDVISLWDQSLQPCVKLTGSVIKQACPKISFDPIPIHY
CTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAE
EEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNDIRKAYCEINGTKWNK
VLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNTTQLF
NNTCIKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNITGI
LLTRDGNTSNETFRPGGGNIKDNWRSELYKYKVVQIE
Ligand information
>4rfn Chain D (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTFCACV
Receptor-Ligand Complex Structure
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PDB4rfn Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.
Resolution3.21 Å
Binding residue
(original residue number in PDB)		A281 S365 G367 D368 E370 I371 W427 G473
Binding residue
(residue number reindexed from 1)		A164 S224 G226 D227 E229 I230 W275 G318
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4rfn, PDBe:4rfn, PDBj:4rfn
PDBsum4rfn
PubMed26085162
UniProtQ0ED31

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