Structure of PDB 4r2c Chain A Binding Site BS01

Receptor Information
>4r2c Chain A (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLT
THIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4r2c Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Resolution1.89 Å
Binding residue
(original residue number in PDB)
R351 E354 R357 R375 R379 H382 H386 T389 R407 E410 R413
Binding residue
(residue number reindexed from 1)
R17 E20 R23 R41 R45 H48 H52 T55 R73 E76 R79
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4r2c, PDBe:4r2c, PDBj:4r2c
PDBsum4r2c
PubMed25258363
UniProtP18146|EGR1_HUMAN Early growth response protein 1 (Gene Name=EGR1)

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