Structure of PDB 4r1e Chain A Binding Site BS01

Receptor Information
>4r1e Chain A (length=142) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVADIQQLKVDESDVRIYFNEKSSGGKISIDNASYNARKLGLAPSSIDEK
KIKELYGDNLTYEQYLEYLSICVHDKDNVEELIKMFAHFDNNCTGYLTKS
QMKNILTTWGDALTDQEAIDALNAFSSEDNIDYKLFCEDILQ
Ligand information
>4r1e Chain B (length=15) Species: 36329 (Plasmodium falciparum 3D7) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GSLLRVQAHIRKKMV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4r1e Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		R100 G103 L104 A105 H136 D139 L144 M147 F148 L168 W171 G172 D173 A174 L175 A183 D201 I202 L203 Q204
Binding residue
(residue number reindexed from 1)		R38 G41 L42 A43 H74 D77 L82 M85 F86 L106 W109 G110 D111 A112 L113 A121 D139 I140 L141 Q142
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4r1e, PDBe:4r1e, PDBj:4r1e
PDBsum4r1e
PubMed25367834
UniProtQ8I4W8

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