Structure of PDB 4qsz Chain A Binding Site BS01

Receptor Information

>4qsz Chain A (length=686) Species: 10090,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALAAAQTNAAAEFAEAALEAVRRALQEFPAAARDLNVPRVV
PYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLSYLRATVGST
EVSVAVTPDGYADAVRGDRFVMPAERRLPISHVLDVLEGRAQHPGVLYVQ
KCSNLPTELPQLLSDIESHVPWASESLGKMPDAVNFWLGDASAVTSLHKD
HYENLYCVVSGEKHFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVVDEE
AMEKVPWIPLDPLAPDLTQYPSYSQAQALHCTVRAGEMLYLPALWFHHVQ
QSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRATGLD

Ligand information

Ligand ID

GLC

InChI

InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChIKey

WQZGKKKJIJFFOK-DVKNGEFBSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.5.0	C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0	C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341	OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341	OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04	OC1C(O)C(OC(O)C1O)CO

Formula

C6 H12 O6

Name

alpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose

PDB chain

4qsz Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4qsz Crystal structure of mouse JMJd7 fused with maltose-binding protein
Resolution	2.86 Å
Binding residue (original residue number in PDB)	D-357 K-356 E-260 Y-216 W-141
Binding residue (residue number reindexed from 1)	D14 K15 E111 Y155 W230
Annotation score	1

Enzymatic activity

Enzyme Commision number

?
1.14.11.63: peptidyl-lysine (3S)-dioxygenase.
3.4.-.-

Gene Ontology

	Molecular Function
GO:0004175	endopeptidase activity
GO:0004177	aminopeptidase activity
GO:0004497	monooxygenase activity
GO:0005515	protein binding
GO:0015144	carbohydrate transmembrane transporter activity
GO:0035064	methylated histone binding
GO:0046872	metal ion binding
GO:0106155	peptidyl-lysine 3-dioxygenase activity
GO:1901982	maltose binding

	Biological Process
GO:0006508	proteolysis
GO:0006974	DNA damage response
GO:0008643	carbohydrate transport
GO:0015768	maltose transport
GO:0018126	protein hydroxylation
GO:0034219	carbohydrate transmembrane transport
GO:0034289	detection of maltose stimulus
GO:0042956	maltodextrin transmembrane transport
GO:0055085	transmembrane transport
GO:0060326	cell chemotaxis

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0030288	outer membrane-bounded periplasmic space
GO:0042597	periplasmic space
GO:0043190	ATP-binding cassette (ABC) transporter complex
GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060	maltose transport complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4qsz, PDBe:4qsz, PDBj:4qsz
PDBsum	4qsz
PubMed
UniProt	P0AEX9\|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE); P0C872\|JMJD7_MOUSE Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (Gene Name=Jmjd7)

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