Structure of PDB 4qqz Chain A Binding Site BS01

Receptor Information
>4qqz Chain A (length=903) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLRPI
TVPPATFTESFPHLSKPNGLQASLAKHLPCLCTGPGLVLITAPMGEGKTE
AAYHVADLLGKATGRPGRFLALPTMATADQMHTRLKEYARYRVEPRSSTL
ALLHSMAWLNPDYAPALGHRDPFAATDWLMGRKRGLLAPWAVGTIDQALM
AVLRAKHNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPV
VLLSATLHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDAR
IGKVTRSSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPL
VKQGGCAAIICTTVAEAQGVYDLLSQWFATLAPDLYLLHSRFPNRQRTEI
TATIVDLFGKEGAQSGRRPTAVLVATQVVEQSLDLDVDLMISDLAPVSLL
LQRAGRCWRHEHLGIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPL
ALLQRTYTLLRRRNGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGE
ELAQRGLARNAVIPDPDDAEDNLNGLTEFSFHVLATRFGAGSVRVLCYYV
DTAGNRWLDPECTVEFPEQGTGREGRFTMADCRDLVARTIPVRMGPWASQ
LTEDNHPPEAWRESFYLRDLVLIPQRVTDEGAVLPTETGGREWLLDPCKG
LIF
Ligand information
Receptor-Ligand Complex Structure
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PDB4qqz Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Resolution2.93 Å
Binding residue
(original residue number in PDB)		K23 H37 D84 K87 H150 D215 W216 S219 E221 T337 M338 H371 S372 R410 T422 D424 T590 T591 V592 S621 R628 T659 Q660 Q664 S730 S733 V734 R828 G832 S833 R884 F906
Binding residue
(residue number reindexed from 1)		K10 H24 D71 K74 H137 D202 W203 S206 E208 T324 M325 H354 S355 R382 T394 D396 T562 T563 V564 S590 R597 T626 Q627 Q631 S693 S696 V697 R787 G791 S792 R843 F865
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qqz, PDBe:4qqz, PDBj:4qqz
PDBsum4qqz
PubMed25132177
UniProtQ47PJ0

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