Structure of PDB 4qep Chain A Binding Site BS01

Receptor Information
>4qep Chain A (length=467) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEPHLKVTKCLRLFNKQYLLCVQAKLSRPDLKGVTEMIKAKAILYPRKII
GDLPGIDVGHRFFSRAEMCAVGFHNHWLNGIDYMSMEYEKEYSNYKLPLA
VSIVMSGQYEDDLDNADTVTYTGQGGHNLTGNKRQIKDQLLERGNLALKH
CCEYNVPVRVTRGHNCKSSYTKRVYTYDGLYKVEKFWAQKGVSGFTVYKY
RLKRLEGQPELTTDEGLVCEDISGGLEFKGIPATNRVDDSPVSPTSGFTY
IKSLIIEPNVIIPKSSTGCNCRGSCTDSKKCACAKLNGGNFPYVDLNDGR
LIESRDVVFECGPHCGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWE
YIPAGSPVCEYIGVVRRTADVNEYIFEIDCPEFCIDAGSTGNFARFINHS
CEPNLFVQCVLSSHQDIRLARVVLFAADNISPMQELTYDYGYALDSVHKV
KQLACYCGALNCRKRLY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qep Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R126 R163 W175 L176 N177 G178 S204 Q206 Y207 D210 Y219 T220 G223 L227 R241 K270 Y273
Binding residue
(residue number reindexed from 1)		R28 R65 W77 L78 N79 G80 S106 Q108 Y109 D112 Y121 T122 G125 L129 R143 K172 Y175
Enzymatic activity
Catalytic site (original residue number in PDB) Y475 Y593
Catalytic site (residue number reindexed from 1) Y361 Y440
Enzyme Commision number 2.1.1.-
2.1.1.367: [histone H3]-lysine(9) N-methyltransferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0042054 histone methyltransferase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:4qep, PDBe:4qep, PDBj:4qep
PDBsum4qep
PubMed25018018
UniProtQ8GZB6|SUVH4_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 (Gene Name=SUVH4)

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