Structure of PDB 4q48 Chain A Binding Site BS01

Receptor Information
>4q48 Chain A (length=500) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LHDRALHLLQTIWGYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQ
LPSLLRPGTGIVVSPLIALMKDQVDTLRQNGVRAAFLNSTLLPHEAREVE
DALLRGDLDLLYVAPERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDF
RPEYQQLSVLAERFPELPRVALTATADERTRADIKSVLRLEDAPQFVSSF
DRPNIQYRVGLKDSPKTQLLHFIREEHPGDAGIVYCLSRKSVEETAKWLQ
AQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVADKPNVRFVAHLD
LPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRMLAQSDAPEEVK
RVEASKLDALLTYCEAATCRRQVLLHYFGEELSEPCGNCDVCLNPPRVRD
LTREAQMALSATIRTGNRFGAAHLTDVLLGRETDKVLAQGHHQLPTFGVG
KEHDEKLWRSVLRQLVSLGYLSADDHFGLRATGKSRGILKEGQKLLLRED
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4q48 Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4q48 Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.
Resolution2.797 Å
Binding residue
(original residue number in PDB)		C381 C401 C404
Binding residue
(residue number reindexed from 1)		C369 C389 C392
Annotation score1
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0009432 SOS response

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Molecular Function
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Biological Process
External links
PDB RCSB:4q48, PDBe:4q48, PDBj:4q48
PDBsum4q48
PubMed25243132
UniProtQ9RUU2

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