Structure of PDB 4q0w Chain A Binding Site BS01

Receptor Information
>4q0w Chain A (length=316) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVHSFWDIAGPTARPVRLESLEDKRMAVDASIWIYQFLKAVRDQNAVKNS
HITGFFRRICKLLYFGIRPVFVFDGGVPVLKRETIRQRKERRQGKREDEV
TMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVF
LFGGTKIYKNMFHEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTN
GLKGMGPVSSIEVIAEFGNLKNFKDWYNNGQFDKRKQETENKFEKDLRKK
LVNNEIILDDDFPSVMVYDAYMRPEVDHDTTPFVWGVPDLDMLRSFMKTQ
LGWPHEKSDEILIPLI
Ligand information
Receptor-Ligand Complex Structure
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PDB4q0w Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		W7 Y36 Q37 K40 D812 D813 S814 K826
Binding residue
(residue number reindexed from 1)		W6 Y35 Q36 K39 D145 D146 S147 K159
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4q0w, PDBe:4q0w, PDBj:4q0w
PDBsum4q0w
PubMed25120270
UniProtP07276|RAD2_YEAST DNA repair protein RAD2 (Gene Name=RAD2)

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