Structure of PDB 4pxg Chain A Binding Site BS01

Receptor Information

>4pxg Chain A (length=466) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TKQAVHNRAKEAVGKSVLELNGGESIKSSVGDAFENWFGVALKATPFKKL
KNGKYSSKERLVLNIINYEKVANENFETSSFLSKNNTIELAFYEYIKGTP
SDNWIIKEAVLYEMHKNPIDYEIIKQDWEIINQYINEGKAHELSEGLTSY
LAPCTKGANASSLRNQPYSDIKAKQRAFSLKSGYMTSILRKYVLGDEKID
SIVKDPFEIKEKSIEDIVFEKFQPYINWSIDKLCEHFSINKGEKGLNYRI
ASAILNLKGKTTKSKPFPEVEEFEKSSIVVKTVHFNKKNVNKESMSFGAF
KFEELANEEWEDSEGYPSAQWRNFLLETRFLFFVVKEDEDGVDIFKGIKF
FSMPEEDINGPVKRMWDDTVKKLKEGVTLEAVPDKSTKDGWRIKNNFVDK
SDDLICHVRPHTNNRDYRGGSNADKLPKKINWINRPDSDDYSDEWMTKQS
FWINNDYIKKQVEDLL

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

4pxg Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4pxg The 2.45 A Crystal Structure of the Restriction Endonuclease Sau3AI Suggests a Self-Inhibition Mechanism
Resolution	2.45 Å
Binding residue (original residue number in PDB)	D462 D463
Binding residue (residue number reindexed from 1)	D439 D440
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Molecular Function

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Biological Process

External links

PDB	RCSB:4pxg, PDBe:4pxg, PDBj:4pxg
PDBsum	4pxg
PubMed
UniProt	P16667\|T2S3_STAAU Type II restriction enzyme Sau3AI (Gene Name=sau3AIR)

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