Structure of PDB 4pw7 Chain A Binding Site BS01
Receptor Information
>4pw7 Chain A (length=197) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLV
LAGGFADEVDRGDEFTYTGSGGKKRIGAPSADQTLTNMNRALALNCDAPL
DDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWP
EISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
Ligand information
>4pw7 Chain C (length=12) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ctggtccggatg
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4pw7
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Resolution
2.001 Å
Binding residue
(original residue number in PDB)
F461 R462 V475 G476 G477 A492 G494 F495 Y507 T508 S510 G511 R520 I521 K569
Binding residue
(residue number reindexed from 1)
F21 R22 V35 G36 G37 A52 G54 F55 Y67 T68 S70 G71 R75 I76 K124
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:4pw7
,
PDBe:4pw7
,
PDBj:4pw7
PDBsum
4pw7
PubMed
24813944
UniProt
Q96PU4
|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)
[
Back to BioLiP
]
