Structure of PDB 4pw6 Chain A Binding Site BS01
Receptor Information
>4pw6 Chain A (length=188) Species:
9606
(Homo sapiens) [
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IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLV
LAGGFADEVDRGDEFTYTGSSADQTLTNMNRALALNCDAPLDDKIGAESR
NWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFL
VWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
Ligand information
>4pw6 Chain C (length=12) [
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gtgatcgaagtt
Receptor-Ligand Complex Structure
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PDB
4pw6
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Resolution
3.789 Å
Binding residue
(original residue number in PDB)
F461 R462 H474 V475 G477 A492 G494 Y507 T508 G509 S510 K569
Binding residue
(residue number reindexed from 1)
F21 R22 H34 V35 G37 A52 G54 Y67 T68 G69 S70 K115
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:4pw6
,
PDBe:4pw6
,
PDBj:4pw6
PDBsum
4pw6
PubMed
24813944
UniProt
Q96PU4
|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)
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