Structure of PDB 4pw5 Chain A Binding Site BS01
Receptor Information
>4pw5 Chain A (length=189) Species:
9606
(Homo sapiens) [
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IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLV
LAGGFADEVDRGDEFTYTGSGGSADQTLTNMNRALALNCDAPLDDKIGAE
SRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHG
FLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGY
Ligand information
>4pw5 Chain C (length=12) [
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ctggtccggatg
Receptor-Ligand Complex Structure
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PDB
4pw5
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Resolution
2.204 Å
Binding residue
(original residue number in PDB)
F461 R462 V475 G476 G477 A492 G494 Y507 T508 G509 S510 G511 K569
Binding residue
(residue number reindexed from 1)
F21 R22 V35 G36 G37 A52 G54 Y67 T68 G69 S70 G71 K117
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:4pw5
,
PDBe:4pw5
,
PDBj:4pw5
PDBsum
4pw5
PubMed
24813944
UniProt
Q96PU4
|UHRF2_HUMAN E3 ubiquitin-protein ligase UHRF2 (Gene Name=UHRF2)
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