Structure of PDB 4pr5 Chain A Binding Site BS01

Receptor Information
>4pr5 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>4pr5 Chain C (length=11) Species: 10376 (human gammaherpesvirus 4) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
HPVGDADYFEY
Receptor-Ligand Complex Structure
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PDB4pr5 A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
Y7 Y59 N63 I66 F67 T69 N70 Y74 S77 N80 Y84 R97 Y99 S116 T143 K146 W147 V152 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y59 N63 I66 F67 T69 N70 Y74 S77 N80 Y84 R97 Y99 S116 T143 K146 W147 V152 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4pr5, PDBe:4pr5, PDBj:4pr5
PDBsum4pr5
PubMed24759101
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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