Structure of PDB 4pps Chain A Binding Site BS01

Receptor Information
>4pps Chain A (length=238) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMIWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pps Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Resolution1.929 Å
Binding residue
(original residue number in PDB)
I358 K362 R363 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K57 R58 L67 V71 E75 D228 L229 E232
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4pps, PDBe:4pps, PDBj:4pps
PDBsum4pps
PubMed24771768
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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