Structure of PDB 4pp6 Chain A Binding Site BS01
Receptor Information
>4pp6 Chain A (length=234) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4pp6 Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4pp6
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Resolution
2.201 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D224 L225 E228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4pp6
,
PDBe:4pp6
,
PDBj:4pp6
PDBsum
4pp6
PubMed
24771768
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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