Structure of PDB 4plm Chain A Binding Site BS01

Receptor Information

>4plm Chain A (length=416) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCGKPPSRYCVVTEKGEEQ
VRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYPHNVTLTLS
LGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNK
PSRAAITKQNEQEAICTDSHTDVRPLSGGLIAFSTLDGRPTAHDFDNSPV
LQDWVTATDIKVTFSRLHTFGDEDDSELARDSYFYAVSDLQVGGRCKCNG
HASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECV
ACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYR
DLSKPISHRKACKECDCHPVGAAGQTCNQTTGQCPCKDGVTGITCNRCAK
GYQQSRSPIAPCIKIP

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

4plm Chain A Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4plm Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Resolution	2.801 Å
Binding residue (original residue number in PDB)	F109 D112 T120 S279
Binding residue (residue number reindexed from 1)	F70 D73 T81 S238
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:4plm, PDBe:4plm, PDBj:4plm
PDBsum	4plm
PubMed	24876346
UniProt	Q90922\|NET1_CHICK Netrin-1 (Gene Name=NTN1)

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