Structure of PDB 4pld Chain A Binding Site BS01

Receptor Information
>4pld Chain A (length=239) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMA
DQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGK
EGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFV
CLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQL
LLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pld Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		F354 R361 D372 M375 L531 M535
Binding residue
(residue number reindexed from 1)		F55 R62 D73 M76 L232 M236
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:4pld, PDBe:4pld, PDBj:4pld
PDBsum4pld
PubMed26553876
UniProtO00482|NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Gene Name=NR5A2)

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