Structure of PDB 4p9z Chain A Binding Site BS01
Receptor Information
>4p9z Chain A (length=109) Species:
9606
(Homo sapiens) [
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EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGN
DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
VPQQPTYVQ
Ligand information
>4p9z Chain B (length=3) Species:
32630
(synthetic construct) [
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YKN
Receptor-Ligand Complex Structure
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PDB
4p9z
Protein-ligand interactions: Probing the energetics of a putative cation-pi interaction.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 S90 S96 Q106 H107 F108 K109 W121
Binding residue
(residue number reindexed from 1)
R14 R33 S35 S37 S43 Q53 H54 F55 K56 W68
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4p9z
,
PDBe:4p9z
,
PDBj:4p9z
PDBsum
4p9z
PubMed
24856058
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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